Comparison of Sunlight Exposure and Vitamin D Supplementation on Serum 25-hydroxyvitamin D Levels

Seoul National University

Status: Completed

Conditions: Cardiometabolic Risk Factors; Vitamin D Deficiency

Treatments: Dietary Supplement: Vitamin D Supplementation; Behavioral: Sunlight Exposure; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03310242

H-1504-112-668

Details and patient eligibility

About

This study aimed to compare the effects between sunlight exposure and oral vitamin D supplementation on serum 25-hydroxyvitamin D concentration and metabolic markers in Korean young adults.

Enrollment: 150 patients

Sex: All

Ages: 18 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Serum 25(OH)vitamin D < 12ng/mL
• age between 18 and 39 years
• Korean men and women

Exclusion criteria

• Vitamin D supplementation within 2 months
• Photosensitivity or UV allergy
• History of hyperparathyroidism/hypercalciuria/kidney stone/skin cancer and other cancer
• Under medication for hypertension, dyslipidemia, and diabetes
• Intake of photosensitive medicine during study period
• Exposure of strong UV (e.g., beach, sun tanning) during study period
• Pregnant/breast-feeding women

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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150 participants in 3 patient groups, including a placebo group

Sunlight Exposure

Experimental group

Description:

Everyday sunlight exposure around noon for 20-30 minutes for 8 weeks

Treatment:

Behavioral: Sunlight Exposure

Vitamin D Supplementation

Experimental group

Description:

Supplementation of vitamin D3 500 IU/day for 8 weeks

Treatment:

Dietary Supplement: Vitamin D Supplementation

Placebo

Placebo Comparator group

Description:

Intake of placebo for 8 weeks

Treatment:

Other: Placebo