Comparison of Surgical Versus Medical Termination of Pregnancy Between 13-20 Weeks of Gestation in Ethiopia

St. Paul's Hospital Millennium Medical College, Ethiopia

Status: Completed

Conditions: Termination of Pregnancy

Treatments: Procedure: Dilation and evacuation

Study type: Interventional

Funder types: Other

Identifiers

NCT04602052

StPaulsHMM

Details and patient eligibility

About

The purpose of the study is to determine the safety and effectiveness of dilation and evacuation for surgical abortion as compared to medical abortion

Full description

All patients with a gestational age between 13-20 weeks are fully counseled on the risks and benefits and given the option of medical or surgical abortion. Those who choose medical abortion receive mifepristone 200 mg on day 1 and are appointed to return to SPHMMC 24-48 hours later for admission and misoprostol administration. Those who chose surgical abortion are given mifepristone 200 mg with or without laminaria and appointed to return the next day for surgical abortion.

Enrollment: 279 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Gestational age between 13 - 20 weeks confirmed with ultrasound,
• Age at or more than18 years,
• Having a working phone and willingness to be contacted for a follow-up questionnaire 2 weeks after the procedure.

Exclusion criteria

• Inability to give consent
• complicated abortion (missed abortion, septic abortion)

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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279 participants in 2 patient groups

Medical arm

Active Comparator group

Description:

Those who choose medical abortion receive mifepristone 200 mg on day 1 and are appointed to return to SPHMMC 24-48 hours later for admission and misoprostol administration.

Treatment:

Procedure: Dilation and evacuation

Surgical arm

Experimental group

Description:

Those who chose surgical abortion are given mifepristone 200 mg with or without laminaria and appointed to return the next day for surgical abortion.

Treatment:

Procedure: Dilation and evacuation