Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension

Dow University of Health Sciences

Status and phase: Unknown; Phase 3

Conditions: Postnatal Hypertension

Treatments: Drug: Labetalol; Drug: Nifedipine

Study type: Interventional

Funder types: Other

Identifiers

NCT02426177

DowUHS

Details and patient eligibility

About

To compare effectiveness of oral labetalol and oral nifedipine for management of postpartum hypertension.

Full description

A comparison of oral labetalol and oral nifedipine for management of postpartum hypertension. Which drug is more effective in lowering blood pressures in patient with postpartum hypertension.

Enrollment: 98 estimated patients

Sex: Female

Ages: 20 to 48 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all women with postpartum hypertension as a continuation of pregnancy induced hypertension,eclampsia, pre-eclampsia or new onset de-novo postpartum hypertension,of any parity.
• age group between 18-48.
• after informed consent.

Exclusion criteria

• all women with chronic hypertension, uncontrolled and un treated medical disorders will be excluded.
• conditions in which drugs labetalol and nifedipine is contraindicated.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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98 participants in 2 patient groups

group A

Active Comparator group

Description:

tab.labetalol is given to the patient with postpartum hypertension in dose of 100 mg 6 hourly increased to maximum 600 mg in 24 hours

Treatment:

Drug: Labetalol

group B

Active Comparator group

Description:

tab.nifedipine is given to the patient with postpartum hypertension in the dose of 10 mg twice a day to maximum dose of 60 mg per 24 hours

Treatment:

Drug: Nifedipine