Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery

Hermann Eye Center

Status: Completed

Conditions: Cataracts

Treatments: Drug: Lidocaine 2% Jelly; Drug: tetracaine 0.5%

Study type: Interventional

Funder types: Other

Identifiers

NCT00827073

HSC-MS-08-0454

Details and patient eligibility

About

The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery. This will be assessed comparing bacterial colony count and species by taking swabs from the eye surface before and after the topical anesthesia has been administered.

Full description

The purpose of this research study is to show that using Lidocaine2% jelly before surgery as an anesthetic (keep you from feeling touch or pain) for cataract surgery does not block the antiseptic (cleans and kills germs) effect of Betadine5%.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• greater or equal to 18 years old
• uni- or bi-lateral visually significant cataracts

Exclusion criteria

• hypersensitivity to betadine5%, topical tetracaine0.5%, or lidocaine2% jelly
• pregnancy

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Tetracaine 0.5% drop

Active Comparator group

Description:

Tetracaine 0.5% drop of betadine will be used on the operative eye after Tetracaine has been administered

Treatment:

Drug: tetracaine 0.5%

Lidocaine 2% Jelly

Active Comparator group

Description:

Lidocaine 2% Jelly drop of betadine will be used on the operative eye after Lidocaine 2% Jelly has been administered

Treatment:

Drug: Lidocaine 2% Jelly