Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual) (PVBS-USguided)

CHU de Reims

Status and phase: Completed; Phase 3

Conditions: Pain

Treatments: Other: paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual).; Other: paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound)

Study type: Interventional

Funder types: Other

Identifiers

NCT02865226

PA15082

Details and patient eligibility

About

Post-thoracotomy pain is one of the most severe. The local analgesia allows its effective control and a reduction of postoperative morbidity and mortality.

The gold standard for local analgesia is the thoracic epidural. However, this technique can be dangerous with severe complications.

The paravertebral block showed comparable efficacy to the thoracic epidural for local analgesia . In addition, it has a better safety profile. There are several installation techniques. The difference in efficiency of these laying techniques is unknown.

Full description

Compare the clinical effectiveness of two strategies of realization of paravertebral block: by the anesthetist before incision (paravertebral block guided by ultrasound) and by the thoracic surgeon at chest closure (paravertebral block visual).

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient with thoracotomy indication for segmentectomy (s), lobectomy (s) lung or pulmonary wedge resection
• patient consenting to participate to the study
• patient enrolled in the national healthcare insurance program
• patient older than 18 years

Exclusion criteria

• patient with neuropathy
• patient with body mass index superior to 35 kg/m2
• patient with contraindication for paravertebral block or local analgesia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

experimental group

Experimental group

Description:

paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound)

Treatment:

Other: paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound)

control group

Active Comparator group

Description:

paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual)

Treatment:

Other: paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual).