Comparison of the Effect of Cervical Mucus Cleaning Method Applied Before Embryo Transfer on Pregnancy Rates.

Zeynep Kamil Maternity and Pediatric Research and Training Hospital

Status: Completed

Conditions: Infertility

Treatments: Procedure: Cannula; Procedure: Cotton swab

Study type: Interventional

Funder types: Other

Identifiers

NCT04888091

90-07.April.2021

Details and patient eligibility

About

To assess the impact of cervical mucus cleansing before embryo transfer and compare two different instruments for this purpose.

Full description

All patients will be informed about the study and those who give written consent will be included in the study.

Women undergoing good quality embryo transfer will be assigned to one of the 3 arms of the study according to the previously determined randomization chart. The first evaluation of the patient will be made on the 12th day after embryo transfer. Pregnancy status will be evaluated with serum βhcg value. If pregnancy is confirmed by serum βhcg value, fetal viability will be evaluated by ultrasound 4 weeks after transfer.

Enrollment: 183 patients

Sex: Female

Ages: 21 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 21-40 years old women,
• Women undergoing good quality embryo transfer,
• Women who are eligible for a single or double embryo transfer.

Exclusion criteria

• If there is a diagnosis of a uterine anomaly,
• If there is a diagnosis of myoma uteri,
• If there is a diagnosis of rheumatological disease,
• Women to be transferred other than good quality embryo,
• Hİstory of previous pelvic, gynecological operation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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183 participants in 3 patient groups

Cervical mucus removal with cotton swab

Active Comparator group

Description:

Cervical mucus will be removed with cotton swab before embryo transfer

Treatment:

Procedure: Cotton swab

Cervical mucus removal with cannula

Active Comparator group

Description:

Cervical mucus will be removed with cannula before embryo transfer

Treatment:

Procedure: Cannula

No cervical mucus removal

No Intervention group

Description:

Cervical mucus will not be removed prior to embryo transfer