Comparison of the Effectiveness of High-Intensity and Low-Intensity Laser Therapies in Primary Knee Osteoarthritis

Ankara City Hospital

Status: Completed

Conditions: Primary Knee Osteoarthritis

Treatments: Device: Conventional Treatment; Device: conventional treatment and high-intensity laser therapy(HILT); Device: conventional treatment and low-intensity laser therapy (LLLT)

Study type: Interventional

Funder types: Other

Identifiers

NCT06825767

E1-20-1087

Details and patient eligibility

About

Our primary goal is to investigate the advantages of low-intensity laser therapy (LLLT) and high-intensity laser therapy (HILT) over conventional therapy in patients with knee osteoarthritis (OA), our secondary goal is to investigate the advantages of HILT and LLLT; to compare its analgesic effects, its effects on functional status and quality of life, and its effects on femoral cartilage thickness.

Full description

In the study, those who applied to Ankara City Hospital Physical Therapy and Rehabilitation Hospital outpatient clinic between 01.10.2020-01.10.2021, were between the ages of 55-75, were diagnosed with primary knee OA according to the American Rheumatology Association, stage 2-3 knee according to Kellgren and Lawrence radiological classification. with OA; 72 volunteer patients with knee pain with a visual pain score of 4 and above for at least 3 months were included. The study was designed as a prospective, randomized, controlled, single-center. Patients were randomly divided into 3 treatment groups. Conventional treatment including hotpack therapy, Transcutaneous Electrical Nerve Stimulation (TENS), joint range of motion exercises, straight leg lifting exercises, quadriceps strengthening exercises, pillow squeezing exercises, balance exercises on one leg for 4 weeks, 3 days a week for 4 weeks in 24 patients in the first group, conventional treatment and HILT were applied to 24 patients in the second group, and conventional treatment and LLLT were applied to 24 patients in the third group. All groups were evaluated clinically and ultrasonographically at the beginning of the treatment, at the end of the treatment and at the 3rd month after the treatment.

Enrollment: 72 patients

Sex: All

Ages: 55 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age range of 55-75 years
• Primary knee OA diagnosis according to ACR (American College of Rheumatology) and Knee OA classified as stage 2-3 according to the KL (Kellgren-Lawrence) radiological classification
• Visual pain score of 4 or higher for knee pain lasting for at least 3 months

Exclusion criteria

• Patients with secondary knee OA
• Patients who have undergone surgical operations related to the knee joint
• Patients with pathology in the hip and/or ankle on the same side
• Patients who have received intra-articular corticosteroid, hyaluronic acid, or PRP injections in the knee joint in the last 6 months
• Patients who have received physical therapy for the knee region in the last 6 months
• Patients with serious systemic diseases such as malignancy, congestive heart failure, or chronic obstructive pulmonary disease
• Patients with insufficient cognitive function

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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72 participants in 3 patient groups

conventional treatment

Active Comparator group

Description:

Conventional treatment including hotpack therapy, Transcutaneous Electrical Nerve Stimulation (TENS), joint range of motion exercises, straight leg lifting exercises, quadriceps strengthening exercises, pillow squeezing exercises, balance exercises on one leg for 4 weeks, 3 days a week for 4 weeks in 24 patients.

Treatment:

Device: Conventional Treatment

conventional treatment and HILT(high-intensity laser therapy)

Active Comparator group

Description:

Conventional treatment and HILT including hotpack therapy, Transcutaneous Electrical Nerve Stimulation (TENS), joint range of motion exercises, straight leg lifting exercises, quadriceps strengthening exercises, pillow squeezing exercises, balance exercises on one leg and HILT for 4 weeks, 3 days a week for 4 weeks in 24 patients .

Treatment:

Device: conventional treatment and high-intensity laser therapy(HILT)

conventional treatment and LLLT(low-intensity laser therapy)

Active Comparator group

Description:

Conventional treatment and LLLT including hotpack therapy, Transcutaneous Electrical Nerve Stimulation (TENS), joint range of motion exercises, straight leg lifting exercises, quadriceps strengthening exercises, pillow squeezing exercises, balance exercises on one leg and LLLT for 4 weeks, 3 days a week for 4 weeks in 24 patients.

Treatment:

Device: conventional treatment and low-intensity laser therapy (LLLT)