Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy

Yonsei University

Status and phase: Completed; Phase 4

Conditions: Gastric Cancer

Treatments: Other: continuous epidural analgesia; Other: continuous intravenous analgesia

Study type: Interventional

Funder types: Other

Identifiers

NCT02458573

4-2015-0157

Details and patient eligibility

About

The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to compare the effect of epidural analgesia and intravenous analgesia on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.

Enrollment: 86 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient between 20 and 70 of age with ASA physical status Ⅰ-Ⅲ
• gastric cancer patient undergoing laparoscopic gastrectomy

Exclusion criteria

• ASA physical status Ⅳ
• bradycardia (< 60 bpm), arrhythmia
• uncompensated heart failure
• hepatic failure (Child-Pugh score B)
• renal failure (eGFR MDRD < 60 ml/min/1.73m2)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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86 participants in 2 patient groups

continuous epidural analgesia group

Experimental group

Treatment:

Other: continuous epidural analgesia

continuous intravenous analgesia group

Active Comparator group

Treatment:

Other: continuous intravenous analgesia