Comparison of the Effects of Different Protein Diet in Hemodialysis Patients

Camillians Saint Mary's Hospital Luodong

Status: Unknown

Conditions: Diffenence of Protein Diets on Hemodialysis Patients

Treatments: Dietary Supplement: protein diet

Study type: Interventional

Funder types: Other

Identifiers

NCT04077918

SMHprotdiet

Details and patient eligibility

About

Chronic hemodialysis (CHD) patients are vulnerable to develop protein energy malnutrition and make a notion that to maintain the nutritional status is of paramount importance in these patients. However, proteins intake from vegetarian and meat diet were observed to have different impacts on nutritional and inflammatory status, mineral homeostasis and its related hormones, and clinical outcomes in non-dialysis CKD patients. In here, we aim to investigate these impacts in CHD patients.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic hemodialysis patient

Exclusion criteria

1. Hemodialysis less than 3 months
2. Age < 20 years or >90 years
3. Serum albumin < 3 g/dL，
4. Daily protein diet < 0.6 gm/kg/day or > 1.2 gm/kg/ day，
5. Cannot obey the diet plan: Gastrectomy, difficult in swallowing
6. Active infection, severe illness: cancer patient, liver cirrhosis, etc.
7. Unable to cooperate in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Plant protein diet

Active Comparator group

Description:

18 g of plant protein diet added every day for 3 months , and after washout for 1 month, 18 g of animal protein diet added every day for 3 months

Treatment:

Dietary Supplement: protein diet

Animal protein diet

Active Comparator group

Description:

18 g of animal protein diet added every day for 3 months, and after washout for 1 month, 18 g of plant protein diet added every day for 3 months

Treatment:

Dietary Supplement: protein diet