Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery

Ondokuz Mayıs University

Status: Completed

Conditions: Chronic Pain; Analgesia; Acute Pain

Treatments: Other: Regional anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04364906

QL20011990

Details and patient eligibility

About

This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia. Spinal anesthesia will be performed to all patients for the surgery.

Full description

In this study, patients are divided into two groups. After the spinal anesthesia is performed and cesarean section surgery is over; QLB 2 block will be performed to patients in Group A ; while QLB 3 block will be performed to patients in Group B.

In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.

Group A - Patients in group A will have QLB 2 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.

Group B - Patients in group B will have QLB 3 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.

Enrollment: 80 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being pregnant for at least 37 weeks
• Planning an elective cesarean operation
• Being between the ages of 18-45

Exclusion criteria

• ASA 3-4 patients with comorbitidies (Serious renal, cardiac, hepatic disease)
• Being operated with general anesthesia
• Obesity (> 100 kg, BMI> 35 kg / m2)
• Contraindication of regional anesthesia (quagulopathy, abnormal INR, thrombocytopenia, infection at the injection site)
• Hypersensitivity to local anesthetics or a history of allergy
• Patients with a history of opioid use longer than four weeks
• Patients with psychiatric disorders
• Patients with anatomic deformity
• Patients who do not want to participate

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups

Quadratus Lumborum Block 2

Active Comparator group

Description:

Quadratus Lumborum Block 2 (QLB 2) will be performed the patients in Group A after the cesarean section surgery. Patient controlled analgesia device (PCA) is used for all the patients in the first 24 hours postoperatively

Treatment:

Other: Regional anesthesia

Quadratus Lumborum Block 3

Active Comparator group

Description:

Quadratus Lumborum Block 3 (QLB 3) will be performed the patients in Group B after the cesarean section surgery. Patient controlled analgesia device (PCA) is used for all the patients in the first 24 hours postoperatively

Treatment:

Other: Regional anesthesia