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Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

B

Bezmialem Vakif University

Status

Completed

Conditions

Bronchiectasis
Cystic Fibrosis

Treatments

Other: Comprehensive Respiratory Physiotherapy

Study type

Interventional

Funder types

Other

Identifiers

NCT04170114
bvuhucgun02

Details and patient eligibility

About

The effect of comprehensive respiratory physiotherapy applications on respiratory function, functional capacity and peripheral muscle strength in children with cystic fibrosis and non-cystic fibrosis will be compared.

Full description

Bronchiectasis may be a congenital cause such as cystic fibrosis (CF) or non-cystic fibrosis such as primary ciliary dyskinesia, post-infectious conditions, aspiration and immunodeficiency; It is a disease characterized by irreversible dilatation of airways. Symptoms; purulent sputum production, chronic cough, hemoptysis, recurrent fever and pleurisy. Mucociliary clearance disorder secondary to inflammation and involvement of exocrine glands in CF plays a major role in the development of symptoms; In non-cystic fibrosis bronchiectasis (NCFB), the development of similar symptoms may occur regardless of these reasons. However, in the examinations of CF, proximal airways; In NCFB, distal airways have been affected more intensively. As part of pulmonary rehabilitation, comprehensive respiratory physiotherapy (CRP) has an important role in the treatment and management of bronchiectasis. Airway cleaning techniques, approaches to reducing respiratory work, and patient education form the basis of CRP and play an active role in the treatment and management of the disease. In the literature, there are studies in which the effects of CRP are given in both CF and NCFB patients and studies comparing evaluation results in both groups without treatment. However, no study was found to compare the efficacy of CRP in these two groups of diseases. Therefore, in this study, the investigators aimed to investigate the differences between the efficacy of CRP among the groups in children with CF and NCFB.

Enrollment

60 patients

Sex

All

Ages

6 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Being between 6-18 years old
  • Clinically diagnosed as cystic fibrosis or non-cystic fibrosis bronchiectasis

Exclusion criteria

  • Previous history of lung or liver transplantation
  • Have had an acute exacerbation in the last month and / or have a history of hospitalization
  • Having a diagnosis of orthopedic problems affecting mobility or a history of musculoskelatal surgery

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups

Cystic Fibrosis
Experimental group
Description:
Children with cystic fibrosis
Treatment:
Other: Comprehensive Respiratory Physiotherapy
Bronchiectasis
Experimental group
Description:
Children with bronchiectasis
Treatment:
Other: Comprehensive Respiratory Physiotherapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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