Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction

Yonsei University

Status: Completed

Conditions: Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia

Treatments: Procedure: Mask ventilation technique; Procedure: High-flow nasal oxygen technique

Study type: Interventional

Funder types: Other

Identifiers

NCT04291339

4-2019-1336

Details and patient eligibility

About

The purpose of this study is to compare the ability of oxygenation with high-flow nasal oxygen therapy and mask ventilation technique for induction of anesthesia in adult patients who are planning to undergo surgery under general anesthesia.

Enrollment: 198 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients aged over 19 years who are scheduled for sleep endoscopy

Exclusion criteria

• basal skull fracture
• facial anomaly
• consciousness disorder
• Risk of aspiration
• necessity of awake fiberoptic intubation due to the large vocal cord mass, endotracheal tumor or bleeding.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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198 participants in 2 patient groups

High-flow nasal oxygen technique

Experimental group

Description:

High-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system during anesthetic induction. Pulse oximetry and oxygen reserve index will be monitored continuously.

Treatment:

Procedure: High-flow nasal oxygen technique

Mask ventilation technique

Active Comparator group

Description:

Oxygen will be supplied through the mouth and nose to the patients using facial mask during anesthetic induction. Pulse oximetry and oxygen reserve index will be monitored continuously.

Treatment:

Procedure: Mask ventilation technique