Comparison of the Efficacy of Irrigation With Epinephrine or Tranexamic Acid on Visual Clarity

Haseki Training and Research Hospital

Status: Completed

Conditions: Rotator Cuff Tears

Treatments: Drug: Epinephrine; Drug: tranexamic acid

Study type: Interventional

Funder types: Other

Identifiers

NCT04628676

saglik bilimleri university

Details and patient eligibility

About

The primary aim of this report is to determine whether there is a difference between Epinephrine and Tranexamic acid in providing visual clarity during arthroscopic rotator cuff tear repair.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Age > 18 years

  • American Society of Anesthesiologist Physical Status Classification System : 1-2
  • Undergoing a full arthroscopic double-row repair due to full-thickness cuff tear
  • Being willing to participate the study

Exclusion criteria

• • Age < 18 years

  • American Society of Anesthesiologist Physical Status Classification System ≥3
  • Concomitant cardiac diseases
  • Concomitant bleeding disorder or coagulopathy
  • Diabetes mellitus
  • Being pregnant
  • Use of contraceptive pills
  • A history of previous shoulder surgery
  • Uncontrolled hypertension during the operation (>180/110 mm Hg)
  • Unrepairable rotator cuff tears
  • Being unwilling to participate the study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

TXA group

Experimental group

Description:

tranexamic acid added to irrigation solution

Treatment:

Drug: tranexamic acid

EPN group

Experimental group

Description:

epinephrine added to irrigation solution

Treatment:

Drug: Epinephrine