Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery

Bakirkoy Dr. Sadi Konuk Training and Research Hospital

Status: Completed

Conditions: Postoperative Complications; Postoperative Pain; Regional Anesthesia Morbidity; Analgesia

Treatments: Procedure: Patients undergoing rectus sheat block and posterior transversus abdominis plane block; Procedure: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT06342076

2023-596

Details and patient eligibility

About

The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for postoperative analgesia in major gynecological cancer surgeries.

The main question(s) it aims to answer are:

[Is subcostal transversus abdominis plane block more effective in postoperative analgesia? ] [Is there a difference in pain scores at 24 hours after surgery? ] Since pain scores within the first 24 hours after surgery will be evaluated, participants will be asked to give a value between 0 and 10 at certain time periods.

Full description

This prospective, randomized study was conducted at Başakşehir Çam and Sakura City Hospital in accordance with the Declaration of Helsinki. After ethics committee approval (decision no: 2023-596, date: 22.11.2023) and written consent from all patients, the study was conducted according to Consolidated Standards of Reporting Trials (CONSORT) guidelines. In the study, which included a total of 50 patients, the patients were divided into two groups: subcostal transversus abdominis plane block (STAPB) or rectus sheath block (RSB). Postoperative 24-hour VAS values, opioid demand and administration amounts in intravenous patient-controlled analgesia, presence of nausea and vomiting, surgical complications and length of hospital stay were evaluated (6th hour, 12th hour, 24th hour).

Enrollment: 50 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• >18 years
• ASA II-III

Exclusion criteria

• Those who are allergic to local anesthetics
• BMI> 40 kg/m2
• Those with chronic pain
• Those with a history of previous abdominal surgery
• Patients who refuse the use of postoperative patient-controlled analgesia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Group1: Subcostal transversus abdominis plane block(STAPB)

Experimental group

Description:

Subcostal transversus abdominis plane block(STAPB)

Treatment:

Procedure: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block

Procedure: Patients undergoing rectus sheat block and posterior transversus abdominis plane block

Group 2: Rectus sheat block(RSB)

Experimental group

Description:

Rectus sheat block(RSB)

Treatment:

Procedure: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block

Procedure: Patients undergoing rectus sheat block and posterior transversus abdominis plane block