Comparison of the Efficacy of Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Enrolling

Conditions: Knee Osteoarthritis

Treatments: Drug: Phenol; Drug: Celestone; Drug: Lidocain

Study type: Interventional

Funder types: Other

Identifiers

NCT06265675

E1-4066/2023

Details and patient eligibility

About

There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block.

Full description

Knee osteoarthritis is one of most frequent reason of knee pain. There are different treatment methods such as analgesic drug treatment, physical therapy techniques, intraarticular injections and neurolysis techniques. In this study, we will compare neurolysis techniques these are phenol block and corticosteroid local anesthetic block.

Enrollment: 88 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with knee osteoarthritis must have pain at least 6 months
• NRS score of knee pain equal or more than 5
• At least grade 3 in Kellgren-Lawrence grading scale
• Non responsive to life style change, weight control, exercises program, medical treatment and the other conservative treatments (physical therapy, intraarticular injections)
• Decreasing at NRS score more than %50 after diagnostic block
• Those who accept the consent form

Exclusion criteria

• Patients who have acute knee injury
• Surgery history in knee
• Connective tissue disease that affect knee
• Sciatica
• Injection story in last 3 months
• Psychiatric or neurologic diseases that affect study
• Septic arthritis, active local or systemic infection
• Coagulopathy
• Pregnancy
• Allergic reaction

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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88 participants in 2 patient groups

Phenol block group

Experimental group

Treatment:

Drug: Phenol

Corticosteroid and local anesthetic

Active Comparator group

Treatment:

Drug: Lidocain

Drug: Celestone