Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation

Yonsei University

Status: Enrolling

Conditions: Liver Cirrhosis; Hepatocellular Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT06767579

4-2024-1084

Details and patient eligibility

About

This study is a prospective observational study that analyzes the incidence of postoperative delirium in patients undergoing liver transplantation, based on the use of the inhalational anesthetic sevoflurane and the intravenous anesthetic propofol.

Enrollment: 350 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 19 years and older
• Patients undergoing liver transplantation who are scheduled to receive anesthesia with the inhaled anesthetic sevoflurane or the intravenous anesthetic propofol.

Exclusion criteria

• Individuals with hearing loss, cognitive impairment or obvious dementia, hepatic encephalopathy, or difficulty in communication.
• Diagnosed with neurological disorders (e.g., brain hemorrhage, stroke, dementia, Parkinson's disease, cognitive impairment, etc.).

Trial design

350 participants in 2 patient groups

Sevoflurane Inhalation Anesthesia Group

Description:

Sevoflurane Inhalation Anesthesia Group in Liver Transplantation Patients

Propofol Intravenous Anesthesia Group

Description:

Propofol Intravenous Anesthesia Group in Liver Transplantation Patients