Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome

American University of Beirut Medical Center

Status: Completed

Conditions: Acute Respiratory Distress Syndrome

Treatments: Diagnostic Test: Obtaining arterial blood gases

Study type: Observational

Funder types: Other

Identifiers

NCT03946189

BIO-2018-0033

Details and patient eligibility

About

In mechanically ventilated patients the PaO2/FiO2 ratio might not be the best reflection of the severity of ARDS. It does not incorporate variables and settings used during mechanical ventilatory support such as the positive end expiratory pressure (PEEP), inspiratory time to expiratory time ratio (Ti:Te), and the peak alveolar pressure (Palv). The aim is to identify a new oxygenation index for stratification of severity of ARDS

Enrollment: 150 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving mechanical ventilation in the Intensive Care Unit.
• Patients in whom the managing medical team requested an arterial blood gas (ABG) analysis.

Exclusion criteria

• Patients in whom arterial blood gas could not be obtained or not ordered.

Trial design

150 participants in 3 patient groups

P/F less than 100

Description:

Patients receiving mechanical ventilation with paO2/FiO2 less than 100

Treatment:

Diagnostic Test: Obtaining arterial blood gases

P/F between 100 and 200

Description:

Patients receiving mechanical ventilation with paO2/FiO2 between 100 and 200

Treatment:

Diagnostic Test: Obtaining arterial blood gases

P/F between 200-300

Description:

Patients receiving mechanical ventilation with paO2/FiO2 between 200 and 300

Treatment:

Diagnostic Test: Obtaining arterial blood gases