Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations

Ankara Etlik City Hospital

Status: Enrolling

Conditions: Mastectomy; Peripheral Nerve Block; Pain Management

Treatments: Procedure: Serratus posterior superior intercostal plane block; Procedure: Thoracic Paravertebral Block

Study type: Interventional

Funder types: Other

Identifiers

NCT06789146

AEŞH-EK-2025-07

Details and patient eligibility

About

Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger chronic pain syndrome.

Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications.

In this study; it was aimed to compare the analgesic effectiveness of serratus posterior superior intercostal plane block and thoracic paravertebral block in the postoperative period in patients who underwent mastectomy.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18-80 years
• American Society of Anesthesiologists (ASA) score I-II-III
• Body Mass Index (BMI) between 18-30 kg/m2

Exclusion criteria

• Patients under 18 and over 80 years of age
• ASA score IV and above
• Patients with a history of bleeding diathesis
• BMI below 18 or above 30 kg/m2

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups

Serratus posterior superior intercostal plane block

Active Comparator group

Description:

After the patients are monitored and in the supine position, after appropriate field sterilization, a serratus posterior superior intercostal plane block will be performed on the patients using 30 ml of local anesthetic solution (0.25% bupivacain) under ultrasound guidance. In the intraoperative period, intravenous analgesics (dexketoprofen 50 mg, tramadol 100 mg) will be given.

Treatment:

Procedure: Serratus posterior superior intercostal plane block

Thoracic Paravertebral Block

Active Comparator group

Description:

After the patients are monitored and in the supine position, after appropriate field sterilization, a thoracic paravertebral block will be performed on the patients using 30 ml of local anesthetic solution (0.25% bupivacain) under ultrasound guidance. In the intraoperative period, intravenous analgesics (dexketoprofen 50 mg, tramadol 100 mg) will be given.

Treatment:

Procedure: Thoracic Paravertebral Block