Comparison of the Systematic Versus the Selective Use of Heparin for the Prevention of Radial Artery Occlusion (EASY-Heparin)

Olivier F. Bertrand

Status: Enrolling

Conditions: Radial Artery Occlusion

Treatments: Other: No heparin

Study type: Interventional

Funder types: Other

Identifiers

NCT06981624

EASY-Heparin

Details and patient eligibility

About

Randomized study comparing the systematic use of heparin (standard of care) against an elective use of heparin to prevent radial artery occlusion after a percutaneous catheterization using a dual-artery compression system.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any patient referred for a diagnostic transradial catheterism

Exclusion criteria

• Unable to understand study design or provide informed consent
• Unable to receive antiplatelet therapy with aspirina and/or clopidogrel-prasugrel and/or ticagrelor and intravenous anticoagulant derived from heparine or bivalirudine
• Local condition such as hematoma or pseudo-aneurims precluding radial or ulnar access.
• Presence of plethysmographic waveform with simultaneous radial and ulnar occlusive compression (due to colaterals or interouseous artery) precluding the evaluation of patent hemostasis.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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500 participants in 2 patient groups

Heparin

No Intervention group

Description:

Standard of care with 70-100 IU/kg of heparin after a diagnostic only trans-radial catheterization and a dual-artery compression device for hemostasis.

No heparin

Experimental group

Description:

No heparin administered after diagnostic only trans-radial catheterization and a dual-artery compression device for hemostasis.

Treatment:

Other: No heparin