Comparison of Three Calcium Supplements

University of Jena

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Calcium carbonate; Dietary Supplement: calcium phosphate; Dietary Supplement: Tricalcium Phosphate; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03286673

H28-06

Details and patient eligibility

About

The study was conducted to investigate the metabolic effects of three different calcium compounds in healthy adults.

Enrollment: 31 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18 - 40 years

Exclusion criteria

• diseases of the gastrointestinal tract
• pregnancy
• the intake of any medication (e. g. for thyroid gland)
• intake of dietary supplements

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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31 participants in 4 patient groups

calcium phosphate

Experimental group

Description:

Pentacalcium hydroxy-triphosphate (Ca5(PO4)3OH) was incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d.

Treatment:

Dietary Supplement: calcium phosphate

Tricalcium Phosphate

Experimental group

Description:

β-tricalcium phosphate (Ca3(PO4)2) as incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d.

Treatment:

Dietary Supplement: Tricalcium Phosphate

Calcium carbonate

Experimental group

Description:

Calcium carbonate (CaCO3) was incorporated in wholemeal and crispy wafer bread in order to achieve a additional calcium intake of 1000 mg/d.

Treatment:

Dietary Supplement: Calcium carbonate

Placebo

Active Comparator group

Description:

Wholemeal and crispy wafer bread without additional calcium additive.

Treatment:

Dietary Supplement: Placebo