Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Civil Hospices of Lyon

Status and phase: Unknown; Phase 3

Conditions: Induction of Total Intravenous General Anesthesia

Treatments: Drug: kétamine 20mg; Drug: ephedrine 3mg; Drug: lidocaine 40mg

Study type: Interventional

Funder types: Other

Identifiers

NCT00146926

2004.367

Details and patient eligibility

About

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion criteria

• pregnant
• sedative or analgesic drug 24h before surgery
• allergy with drug used in the study
• difficulty of communication
• absence of informed written consent