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Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

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Civil Hospices of Lyon

Status and phase

Unknown
Phase 3

Conditions

Induction of Total Intravenous General Anesthesia

Treatments

Drug: kétamine 20mg
Drug: ephedrine 3mg
Drug: lidocaine 40mg

Study type

Interventional

Funder types

Other

Identifiers

NCT00146926
2004.367

Details and patient eligibility

About

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion criteria

  • pregnant
  • sedative or analgesic drug 24h before surgery
  • allergy with drug used in the study
  • difficulty of communication
  • absence of informed written consent

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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