Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study

University of Granada (UGR)

Status: Not yet enrolling

Conditions: Oral Surgery; Third Molar Extraction; Oral Infection; Wound Healing Complication

Treatments: Other: To Compare 3 different suture materials used in oral surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT06864559

2028/CEIH/2021

Details and patient eligibility

About

Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used in Oral Surgery (Silk, non-absorbable polyamide monofilament and non-absorbable expanded polytetrafluoroethylene).

Full description

The general or primary objective is:

• To compare 3 non-absorbable suture materials used in oral surgery: silk, polyamide monofilament and expanded polytetrafluoroethylene.

The specific or secondary objectives are:

• To evaluate how each type of suture influences wound healing and the patient's postoperative period.
• To study bacterial colonization in each type of suture.
• To determine the tissue reaction and clinical characteristics of each suture.

Enrollment: 24 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with indication for extraction of a third lower molar retained in an unfavorable position that requires a bayonet incision in the surgical procedure.
• Age: patients aged 18 years or older.
• ASA I patients (Classification of the American Society of Anesthesiology, 1979): healthy patients who tolerate stress well, without systemic pathology, no anxiety and in whom a therapeutic modification is not necessary.

Exclusion criteria

• Pregnant or breastfeeding women.
• Smoking patients.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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24 participants in 3 patient groups

Suture 1: Silk.

Other group

Description:

Silk suture.

Treatment:

Other: To Compare 3 different suture materials used in oral surgery

Suture 2: Non-absorbable polyamide monofilament.

Other group

Description:

Non-absorbable polyamide monofilament.

Treatment:

Other: To Compare 3 different suture materials used in oral surgery

Suture 3: Non-resorbable expanded polytetrafluoroethylene.

Other group

Description:

Non-resorbable expanded polytetrafluoroethylene.

Treatment:

Other: To Compare 3 different suture materials used in oral surgery