Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss (FPHL)

Sohag University

Status and phase: Completed; Phase 4

Conditions: Female Pattern Hair Loss

Treatments: Other: Placebo (Ethanol); Drug: Topical minoxidil 5% in 90% ethanol and 5% propylene glycol; Drug: Topical minoxidil 5% in pure ethanol alone

Study type: Interventional

Funder types: Other

Identifiers

NCT04090801

5/2015

Details and patient eligibility

About

The study will be included 60 women with FPHL. The diagnosis of FPHL will be established by clinical (Ludwig classification) and trichoscopic evaluation of frontal and occipital regions of the scalp.

Full description

Enrolled women will be randomly assigned into 3 treatment groups: group A will apply topical minoxidil 5% in 90% ethanol and 5% propylene glycol, group B will apply topical minoxidil 5% in pure ethanol alone and group C will apply pure ethanol (placebo) twice daily.

The treatment will be continued for six months with regular visits at 3 months intervals.

The medications will be provided in bottles which were identical in shape and color, and were coded by a third party.

Both patients and investigator will be blinded to the medication. Disclosure of the codes will be done, by a third party, at the end of the study.

Enrollment: 60 patients

Sex: Female

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• FPHL

Exclusion criteria

• No

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 3 patient groups, including a placebo group

Topical minoxidil 5% in 90% ethanol and 5% propylene glycol

Active Comparator group

Description:

Group A applied topical minoxidil 5% in 90% ethanol and 5% propylene glycol

Treatment:

Drug: Topical minoxidil 5% in 90% ethanol and 5% propylene glycol

Topical minoxidil 5% in pure ethanol alone

Active Comparator group

Description:

Group B applied topical minoxidil 5% in pure ethanol alone

Treatment:

Drug: Topical minoxidil 5% in pure ethanol alone

Placebo

Placebo Comparator group

Description:

Group C applied pure ethanol (placebo)

Treatment:

Other: Placebo (Ethanol)