Comparison of Treatment Effect of Chinese Medicine and Western Medicine on Depression in China and America

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Status: Unknown

Conditions: Depression

Treatments: Drug: Chinese herbs; Device: Transcranial magnetic stimulation; Procedure: acupuncture; Other: Psychotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01558154

2011DFA30960

Details and patient eligibility

About

Comparison of different assessment methods to evaluate the treatment efficacy of Chinese medicine on minor and mild depression.

Full description

Significant differences show on the evaluation of treatment efficacy of Chinese medicine on depression in China and America. Choose minor and mild depression patients as trials. One hundred and sixty trials will be included and randomly divided into Chinese medicine group (n=40), acupuncture group (n=40), traditional Chinese medicine psychology group (n=40) and physical treatment group (n=40). Time points of assessment are before treatment, 1 week, 2 weeks, 4weeks, 6 weeks and 12 weeks post treatment.The assessment tools are series of psychological questionnaires. And study the mechanism of treatment efficacy assessment variances by different methods.

Enrollment: 160 estimated patients

Sex: All

Ages: 16 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• According with ICD-10 criteria of depression;
• Age 16-70;
• Antidepressant and other Psychiatric drugs have not been had two weeks before the trial, or the drugs above had been used but have cleaning period of two weeks;
• Level of education is higher than junior middle school;
• Course of disease is more than two weeks;
• Volunteer to join and Signed the informed consent

Exclusion criteria

• Pregnancy or lactation;
• Severe depression or have serious suicidal tendencies
• long distance or other causes who can not adherence to treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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160 participants in 4 patient groups

Chinese herb

Experimental group

Description:

Chinese herbs special for depression

Treatment:

Drug: Chinese herbs

acupuncture

Experimental group

Treatment:

Procedure: acupuncture

Psychotherapy

Experimental group

Treatment:

Other: Psychotherapy

physiotherapy

Experimental group

Treatment:

Device: Transcranial magnetic stimulation