Comparison of Treatment of Recurrent HCC With Repeat Hepatectomy,and TACE With AFP Conversion (HCCTACEAFP)

N

Naval Military Medical University (Second Military Medical University)

Status

Completed

Conditions

Recurrent Hepatocellular Carcinoma

Treatments

Procedure: Hepatectomy
Procedure: TACE

Study type

Interventional

Funder types

Other

Identifiers

NCT02728219
2012ZX10002016007002

Details and patient eligibility

About

The purpose of this study is to compare the treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion.

Full description

Though many HCC patients have been benefited from hepatectomy treatment, still the high recurrence rate after the hepatectomy led to limited effectiveness. This is the first study in same case system on comparison of effectiveness among repeat hepatectomy, and TACE with AFP conversion.

Enrollment

150 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. via clinical diagnosis and confirm it is early recurrent liver cancer with AFP conversion, and not accept any anticancer treatment.
  2. age:18-70years
  3. better liver function (Child-Pugh,class A or B)

Exclusion criteria

  1. reject to attend;
  2. impossible to come to our hospital for physical examination regularly.
  3. cancer epitome、seed focus、lymph node or distant metastasis
  4. Blood clotting function hindrance;
  5. serious heart、lung、kidney disease

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

150 participants in 2 patient groups

hepatectomy
Experimental group
Description:
Comparison of Treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion
Treatment:
Procedure: TACE
TACE
Active Comparator group
Treatment:
Procedure: Hepatectomy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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