Comparison of Two Application Techniques for LET Gel

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Status and phase

Completed

Phase 4

Conditions

Lacerations

LET

Pain, Procedural

Treatments

Drug: LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel

Study type

Interventional

Funder types

Other

Identifiers

NCT04203225

30846-01

Details and patient eligibility

About

Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs. once for 30 minutes prior to suturing simple lacerations in children aged 7-17 years.

Full description

Randomized single-blinded clinical trial with convenience sampling of the anesthetic efficacy of a single 30-minute application vs three 10-minute applications of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) prior to suturing simple lacerations in children aged 7-17 years seen in the Emergency Department.

Enrollment

48 patients

Sex

All

Ages

7 to 17 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Simple <= 3cm lacerations requiring suturing (as decided by clinician care providers)
Plan to suture with simple interrupted sutures

Exclusion criteria

Lacerations involving the hands, feet, genitals, tongue, mucus membranes, nose, ears, or occurring over joints
Patients whose primary language was neither English nor Spanish
Developmentally delayed or disabled patient such that they were unable to give a pain score
Patients requiring procedural sedation or anxiolysis with oral or intranasal midazolam