Comparison of Two Laser Therapy Methods for PDR

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 2

Conditions: Proiriftrative Diabetic Retinopathy

Treatments: Procedure: conventional prp; Procedure: targeted prp

Study type: Interventional

Funder types: Other

Identifiers

NCT01232179

88100

Details and patient eligibility

About

Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly. However , the treatment may also resulting adverse effects such as blurring of central vision, visual field constriction and disturbance in dark adaptation and contrast vision. Extended targeted retinal coagulation (TRP) to the ischemic areas may cause regression of the neovascularization while minimizing some of the risks and complication associated of treatment of PDR with these two methods.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with PDR condidate for photocoagulation teraphy
• Pupil with dilatasion≥6mm
• without privious treatment with anti VEGF drugs 3months before study
• without privious vitroretinal sugery
• without privoius lasertraphy

Exclusion criteria

• To have NVI cricteria with increase of inraocular pressure
• to have cataract or vitrus leakage which prevent lasertraphy
• pupil smaller that 6mm
• traditional retinal detachment
• privious treatment with anti VEGF drugs 3months before study
• privious PRP
• patient unable to get wide field FAG

Trial design

0 participants in 2 patient groups

conventional prp

Active Comparator group

Treatment:

Procedure: conventional prp

targeted PRP

Active Comparator group

Treatment:

Procedure: targeted prp