Comparison of Two Methods for Bowel Preparation in Patients With Constipation

Air Force Military Medical University of People's Liberation Army

Status: Unknown

Conditions: Health Behavior

Treatments: Drug: Three times dose of 4L PEG; Drug: Split dose of 4L PEG

Study type: Interventional

Funder types: Other

Identifiers

NCT03306030

KY20172055-2

Details and patient eligibility

About

Constipation is a common high risk factor for inadequate bowel preparation. The bowel cleansing efficacy of the standard split-does of 4L seems to be suboptimal in constipated patients. The investigator hypothesized that compared with the standard preparation regime, the split-dose with three times of 4L PEG may be superior in BP quality.

Enrollment: 140 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18-80 with constipation.

Exclusion criteria

• History of colorectal surgery BMI>30 Suspected colonic stricture or bowel obstruction Use of purgatives within 3 days Pregnancy or lactation Unable to give informed consent Haemodynamically unstable

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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140 participants in 2 patient groups

Split group

Active Comparator group

Description:

Split-dose of 4l PEG was used before and on the day of colonoscopy

Treatment:

Drug: Split dose of 4L PEG

Three times group

Experimental group

Description:

Three times-dose of 4l PEG was used before and on the day of colonoscop of 4l PEG was used before and on the day of colonoscopy

Treatment:

Drug: Three times dose of 4L PEG