Comparison of Two Physical Activity Interventions in Individuals With Multiple Sclerosis

Kessler Foundation

Status: Enrolling

Conditions: Multiple Sclerosis

Treatments: Behavioral: Stretching Program; Behavioral: Aquatic Exercise Program

Study type: Interventional

Funder types: Other

Identifiers

NCT02496416

R-876-15

Details and patient eligibility

About

This study will examine the effectiveness of aquatic therapy on a range of MS-related symptoms such as cognition, mood, fatigue and quality of life (QOL).

Full description

Aim 1. Examine the impact of aquatic exercise on cognitive abilities. The proposed study will test the hypotheses that, compared to the wait-list control group, the treatment group will demonstrate significantly greater improvements in cognitive outcomes, specifically: processing speed, executive functioning, working memory and long-term memory.

Aim 2. The current study will examine the impact of an aquatic exercise on fatigue, mood, wellness, QOL and physical functioning. Specifically the investigators predict that aquatic exercise will lead to improvements in: 1.Fatigue 2. Health related QOL 3. Depression/anxiety 4. Self-efficacy 5. Physical Functioning (i.e. gait and walking).

Aim 3: Examine the long-term effects of aquatic exercise on all outcome measures.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of MS.
• between the ages of 18-65.
• read and speak English fluently.

Exclusion criteria

• history of significant substance abuse.
• history of neurological disease other than MS (for example, stroke, epilepsy, or brain injury).
• history of significant psychiatric illness (for example, bipolar disorder or schizophrenia).
• has engaged in more than 30 minutes of moderate to strenuous exercise per week during the past six months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 2 patient groups

Treatment

Experimental group

Description:

The treatment group will participate in an eight week aquatic exercise program during weeks 2-9 of the study. The aquatic exercise program will consist of 45 minute classes held 3 days/week for 8 weeks (18 hours total). The program is based on guidelines provided by the National Multiple Sclerosis Society (NMSS) and will be led by an aquatic fitness instructor certified to teach individuals with MS at the YMCA in Randolph, NJ.. The exercises will focus on improving flexibility, balance and strength. Equipment such as water mitts, paddles, noodles and bands will be used to increase the level of difficulty as needed.

Treatment:

Behavioral: Aquatic Exercise Program

Control

Active Comparator group

Description:

The control group will participate in an eight week stretching program during weeks 2-9 of the study. The stretching program will consist of 45 minute classes held 3 days/week for 8 weeks (18 hours total). The program is based on guidelines provided by the National Multiple Sclerosis Society (NMSS) and will be conducted online via a secure video-conferencing website.

Treatment:

Behavioral: Stretching Program