Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke

Hospital Sao Domingos

Status and phase: Unknown; Phase 4

Conditions: Acute Ischemic Stroke

Treatments: Other: Carbohydrate restrictive strategy; Drug: Intensive insulin therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00747279

HSD001

Details and patient eligibility

About

The purpose of this prospective randomized controlled trial was to compare intensive insulin therapy with a carbohydrate restrictive strategy in patients with acute ischemic stroke evaluating the outcome through the Glasgow Outcome Scale Extended, hospital mortality and NIHSS during the ICU stay.

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients with acute ischemic stroke defined as: Abrupt onset of focal neurologic deficit
• No evidence of intracranial hemorrhage at non-contrasted CT scan.

Exclusion criteria

• Age below 18
• Pregnancy

Trial design

70 participants in 2 patient groups

1

Experimental group

Description:

Carbohydrate restrictive strategy

Treatment:

Other: Carbohydrate restrictive strategy

2

Active Comparator group

Description:

Intensive insulin therapy

Treatment:

Drug: Intensive insulin therapy