Comparison of Vitrectomy Without Internal Limiting Membrane Peeling Versus Inverted ILM Flap Technique for Macular Hole Retinal Detachment in Highly Myopic Eyes

University of Alexandria

Status: Completed

Conditions: Retina Detachment; Macular Holes

Treatments: Procedure: vitrectomy with or without inverted ILM flap technique

Study type: Interventional

Funder types: Other

Identifiers

NCT04011007

31241

Details and patient eligibility

About

The aim of this study was to determine whether inverted ILM peeling technique could contribute to high reattachment and closure rates after vitrectomy in patients with myopic macular hole retinal detachment (MHRD) in comparison to no ILM peeling.

This retrospective study will include 40 patients presenting by myopic macular hole retinal detachment. Exclusion criteria will include history of trauma, choroidal neovascularization, and the presence of a peripheral retinal break or proliferative vitreoretinopathy before the initial surgery.

Subjects will be divided into 2 groups; Group 1 will include 20 patients that were treated by vitrectomy without ILM peeling and postoperative gas or silicone oil tamponade with or without cataract surgery.

Group 2 will include 20 patients that were treated by vitrectomy with ILMflap technique and postoperative gas or silicone oil tamponade with or without cataract surgery.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: macular hole retinal detachment in high myopic eyes.

Exclusion Criteria:

• eyes with previous vitreoretinal surgery, trauma, diabetic retinopathy, retinal vein occlusion, uveitis, and other retinal diseases were excluded.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

vitrectomy without ILM peeling

Active Comparator group

Description:

vitrectomy without ILM peeling

Treatment:

Procedure: vitrectomy with or without inverted ILM flap technique

vitrectomy with inverted ILM flap technique

Active Comparator group

Description:

vitrectomy with inverted ILM flap technique

Treatment:

Procedure: vitrectomy with or without inverted ILM flap technique