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Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension

U

Ufuk University

Status and phase

Completed
Phase 4

Conditions

Oxygen Saturation

Treatments

Drug: Sevoflurane
Drug: Desflurane

Study type

Interventional

Funder types

Other

Identifiers

NCT02834845
2016Sept

Details and patient eligibility

About

Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation. On this account, the investigators aim to investigate the effects of different volatile anesthetics combined with a short-acting opioid on cerebral oxygenation during controlled hypotension using near infrared spectroscopy.

Enrollment

95 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients in American Society of Anesthesiology (ASA) classification I and II
  • Patients undergoing elective septoplasty operation

Exclusion criteria

  • Patients in ASA classification III and higher
  • Emergency surgery
  • Patients in New York Heart Association classification III-IV
  • Patients with known allergy to drugs used in the study

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

95 participants in 2 patient groups

Sevoflurane
Experimental group
Treatment:
Drug: Sevoflurane
Desflurane
Experimental group
Treatment:
Drug: Desflurane

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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