Comparison of Volume Controlled Ventilation and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum

Yonsei University

Status: Completed

Conditions: Robot-assisted Laparoscopic Radical Prostatectomy Undergoing General Anesthesia

Treatments: Other: Autoflow-volume controlled ventilation; Other: Volume controlled ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT02803424

4-2016-0311

Details and patient eligibility

About

The steep trendelenburg position and pneumoperitoneum during laparoscopic surgery have the potential to cause an adverse effects on respiratory mechanics and gas exchange. Autoflow-volume controlled ventilation may improve lung compliance and reduce airway peak pressure. Therefore, the aim of this study is to evaluate whether Autoflow-volume controlled ventilation improves gas exchange and respiratory mechanics in patients undergoing robot-assisted laparoscopic radical prostatectomy.

Enrollment: 80 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adult male patients scheduled for elective robot-assisted laparoscopic radical prostatectomy undergoing general anesthesia

Exclusion criteria

1. chronic obstructive respiratory diseases
2. heart failure
3. body mass index (BMI >30 kg/m2)

Trial design

80 participants in 2 patient groups

Volume controlled ventilation

Experimental group

Description:

During the steep trendelenburg position and pneumoperitoneum, volume controlled ventilation will be applied with 8ml/kg (ideal body weight) and inspiration:expiration ratio (I:E) = 1:2.

Treatment:

Other: Volume controlled ventilation

Autoflow-volume controlled ventilation

Active Comparator group

Description:

During the steep trendelenburg position and pneumoperitoneum, Autoflow-volume controlled ventilation will be applied with 8ml/kg (ideal body weight) and inspiration:expiration ratio (I:E) = 1:2.

Treatment:

Other: Autoflow-volume controlled ventilation