Comparison of Volume Controlled Ventilation With 1:1 Inspiratory to Expiratory Ratio and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum

Yonsei University

Status: Completed

Conditions: Robot Assisted Laparoscopic Prostatectomy

Treatments: Procedure: ventilation strategy 1; Procedure: ventilation strategy 2

Study type: Interventional

Funder types: Other

Identifiers

NCT03202953

4-2017-0400

Details and patient eligibility

About

The purpose of this study is to compare the 1: 1 I: E ratio VCV and the autoflow VCV in patients undergoing robot assisted laparoscopic prostatectomy

Enrollment: 78 patients

Sex: Male

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. adult (20-80 years old)
2. patients undergoing robot assisted laparoscopic prostatectomy

Exclusion criteria

1. history of COPD
2. decreased heart function (EF <50%)
3. BMI>30
4. patients who cannot read the consent form (e.g., blind, foreigner)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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78 participants in 2 patient groups

1:1 I:E ratio VCV (Group I)

Experimental group

Description:

volume controlled ventilation with 1:1 inspiratory to expiratory ratio After trendelenburg position, Tidal volume : 8ml/kg, inspiration:expiration ratio = 1:1, FiO2 = 0.5, maintain end tidal CO2 around 40±5 mmHg. Positive end expiratory pressure will not used.

Treatment:

Procedure: ventilation strategy 1

autoflow VCV (Group A)

Active Comparator group

Description:

autoflow volume-controlled ventilation After trendelenburg position, Tidal volume : 8ml/kg, inspiration:expiration ratio = 1:2, FiO2 = 0.5, maintain end tidal CO2 around 40±5 mmHg. Positive end expiratory pressure will not used.

Treatment:

Procedure: ventilation strategy 2