Comparisons of Urodynamic, Bladder Diary, Quality of Life Parameters Between OAB-wet and OAB-dry Female Patients

National Taiwan University

Status: Completed

Conditions: Urinary Bladder, Overactive

Study type: Observational

Funder types: Other

Identifiers

NCT03560778

201404012RINC

Details and patient eligibility

About

A small bladder capacity and more frequent urgency episodes were predictors of OAB-wet, and the above findings might indicate that OAB-wet and OAB-dry are a continuum of OAB. Older age, high maximum flow rate, high detrusor pressure at maximum flow rate and the presence of urodynamic stress incontinence were also independent predictors for OAB-wet, and the above might indicate that OAB-wet and OAB-dry have at least partly different underlying pathophysiologies.

Full description

Aims: To identify factors predicting the presence of OAB-wet and to further derive the underlying pathophysiology in OAB-wet vs. OAB-dry.

Methods: Between September 2007 and September 2013, the medical records of women with OAB who completed a 3-day bladder diary and underwent urodynamic studies in a tertiary referral center will be reviewed. OAB-wet will be diagnosed in patients who complained of at least one episode of urgency incontinence in the previous month; otherwise, OAB-dry is diagnosed. Multivariate logistic regression analysis will be used to predict the presence of OAB-wet.

Enrollment: 623 patients

Sex: Female

Ages: 20 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. The diagnosis of overactive bladder disease
2. Female patient of more than 20 year-old

Exclusion criteria

1. Dominant symptoms with stress urinary incontinence (SUI)
2. Regular urethral catheterization or intermittent self-catheterization
3. Urinary tract infection or chronic inflammation in the previous 2 weeks
4. Bladder calculus
5. A history of pelvic radiotherapy
6. A preexisting malignant pelvic tumor.