Complex-Posttraumatic Stress Disorder in Urban Egypt: Pilot Testing of a Culturally-adapted Evidence-Based Treatment Manual and Development of a Culture-specific Diagnostic

University of Lausanne (UNIL)

Status

Enrolling

Conditions

Complex Post-Traumatic Stress Disorder

Treatments

Behavioral: Enhanced Skills Training in Affective and Interpersonal Regulation

Study type

Interventional

Funder types

Other

Identifiers

NCT06464432

052024_00001

2023-2024-204 (Other Identifier)

Details and patient eligibility

About

Background: The CPTSD diagnosis presented in the ICD-11 is supposed to provide core and culturally invariant symptoms, which is supported by recent research. Yet, evidence also shows the necessity of integrating culture-specific symptoms in intervention and diagnostic tools to enhance the validity and efficacy of such diagnoses and therapeutic interventions. Along with cultural aspects, there are relevant structural aspects e.g., economic, and social inequalities, which impact mental health. These aspects remain understudied in low middle income countries like Egypt, where there are considerable rates of violence.

Aims: The project aims to i) culturally adapt and pilot test the therapeutic manual ESTAIR/MPE in urban Egypt, and ii) to pilot test a cultural and structural module for the diagnostic assessment of CPTSD among the same target population. The objective is to assess the feasibility, acceptability, and initial impact on clinical outcomes of both the manual and diagnostic modules.

Methods: In earlier phases, the project gathered qualitative data from key informants on the cultural and structural dimensions of CPTSD in urban Egypt. Using the collected data, investigators culturally adapted this intervention and developed a diagnostic cultural module. Subsequently, the investigators will pilot-test it in four groups of five participants each, 20 participants in total. The project intends to collect both quantitative and qualitative measures to explore determined outcomes and analyze them accordingly.

Full description

For further information, please see the attached protocol.

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Egyptian
18 years of age or older
Literate, can give written or oral consent
History of severe and/or prolonged trauma, and screen positive for CPTSD
Reside in any other major city

Exclusion criteria

Imminent risk of suicide, psychotic symptoms, and/or severe alcohol and/or drug abuse
Have been in therapy before (i.e., completed more than 5-10 sessions of psychotherapy)