Compliance of Diabetic Patients Treated With Metformin (CODAMET)

Institute for Clinical and Experimental Medicine

Status: Unknown

Conditions: Type 2 Diabetes Mellitus

Treatments: Diagnostic Test: Measurement of plasma metformin levels

Study type: Observational

Funder types: Other

Identifiers

NCT03864705

001

Details and patient eligibility

About

Metformin is the 1st line treatment in all subjects with type 2 diabetes without a contraindication to its use. The compliance with the use of metformin is not optimal mainly owing to relatively frequent gastrointestinal side effects. However, hard data about the real compliance are currently not available.

In this trial we aim at assessing the compliance with metformin intake using a combination of serum metformin measurement and a specific questionnaire. We will further evaluate the impact of different pharmacological forms of metformin (standard vs. XR - extended release) on its compliance and try to identify common characteristics associated with reduced compliance.

Enrollment: 400 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetes mellitus on metformin therapy for at least 3 months

Exclusion criteria