Complications Associated With Central Venous Access in the NSICU: PICC vs CVC (NSPVC)

Penn State Health

Status: Completed

Conditions: Neuroscience ICU; PICC; Neuro ICU; CVC; Central Line; Central Venous Catheter

Treatments: Device: peripherally inserted central catheter; Device: centrally inserted central catheter

Study type: Interventional

Funder types: Other

Identifiers

NCT02314520

STUDY00000582

Details and patient eligibility

About

The goal of this study is to determine whether Peripherally Inserted Central Catheter or Centrally Inserted Venous Catheters have lower complication rates in the Neuroscience Intensive Care Unit. After admission to the Neuroscience ICU and if they require central access, patients will be randomized to receive a PICC or CVC and complications (such as pneumothorax, deep venous thrombosis, infection, etc.) will be tracked and compared between the two interventions.

Enrollment: 152 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Adult patients admitted to the NSICU, who require central access for the treatment of their illness.

Exclusion criteria

1. Current or recent (within 1 month) diagnosis of bacteremia
2. Current or recent (within 1 year with confirmed resolution by imaging) deep venous thrombosis
3. Existing central access
4. Non-English speaking
5. Requirement for emergent central access and unable to obtain consent in an emergency setting

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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152 participants in 2 patient groups

PICC

Active Comparator group

Description:

Patients randomly assigned to receive a peripherally inserted central catheter and they will be monitored for either having a complication or no complication.

Treatment:

Device: peripherally inserted central catheter

CVC

Active Comparator group

Description:

Patients randomly assigned to receive a centrally inserted central catheter and they will be monitored for either having a complication or no complication.

Treatment:

Device: centrally inserted central catheter