Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma"

Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

Status: Active, not recruiting

Conditions: Gallbladder Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT05222854

CONGENIAL

Details and patient eligibility

About

Multicenter German- Registry of Incidental Gallbladder Carcinoma combining clinical real-world data and comprehensive genomic profiling. The registry collects medical data from clinical observation and molecular data derived from archival tumor tissue samples but does not define any medical intervention nor does it evaluate the efficacy or safety of the treatment decision made by the investigator.

Full description

In the largest cohort of IGBC patients ever analysed in such a comprehensive approach

• determine the course of patients in this rare kind of cancer
• combine cGP analysis of histological tumor samples with clinical real-life data to get a comprehensive overview on IGBC patients analysed and evaluate data to identify possible further (targeted) treatment possibilities
• analyze potential risk factors associated with gallbladder carcinoma
• assess the frequency of targetable mutations in IGBC

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Histologically confirmed diagnosis of incidental gallbladder carcinoma

• Patient ≥ 18 years old
• Patient already deceased
• Available tumor tissue (FFPE block)

Exclusion criteria

Patient under 18 years of age