Comprehensive Geriatric Assessment in Kidney Transplantation (CoGeriaTx)

Institute for Clinical and Experimental Medicine

Status: Enrolling

Conditions: Frailty Syndrome; Kidney Transplant; Complications; Depressive Syndrome

Treatments: Procedure: Functional geriatric assessment

Study type: Observational

Funder types: Other

Identifiers

NCT06104696

Geriatrics

Details and patient eligibility

About

This observational study aims to analyze the results of comprehensive geriatric assessment and to monitor the development of functional status in geriatric kidney transplant candidates and recipients.

Full description

Kidney transplantation represents the best therapeutical option in patients in end stage kidney disease. At present, increasing number of older patients are referred for kidney transplantation. Patients' functional status has been shown to be associated with transplant outcomes.

The comprehensive geriatric assessment (CGA) of functional and mental status in older kidney transplant candidates might play an important and supportive role in the pre-transplant evaluation process, including acceptance for transplantation. In kidney transplant recipients, this examination might be useful to evaluate the impact of pre-transplant status on post-transplant course. Also in KTR, CGA may contribute to the improvement of functional status and quality of life independently from the graft function.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• kidney transplant candidates aged 60+ years
• kidney transplant recipients aged 60+ years

Exclusion criteria

• kidney transplant candidates aged below 60 years
• kidney transplant recipients aged below 60 years

Trial design

1,000 participants in 3 patient groups

Non-frail

Description:

Group of patients which will meet the criteria for non-frail according to the result of functional examination.

Treatment:

Procedure: Functional geriatric assessment

Pre-frail

Description:

Group of patients which will meet the criteria for pre-frail according to the result of functional examination.

Treatment:

Procedure: Functional geriatric assessment

Frail

Description:

Group of patients which will meet the criteria for frail according to the result of functional examination.

Treatment:

Procedure: Functional geriatric assessment