Comprehensive Study on the Quality of Life in Cervical Cancer Patients

Lei Li

Status: Unknown

Conditions: Ovarian Reserve Function; Pelvic Floor Disorders; Urodynamics; Disease-free Survival; Quality of Life; Survivorship; Overall Survival; Rectum Dynamics; Cervical Cancer; Sex Dysfunction

Treatments: Diagnostic Test: ovarian reserve function; Diagnostic Test: Rectum dynamics testing; Diagnostic Test: Urodynamic testing; Diagnostic Test: questionnaires survey

Study type: Observational

Funder types: Other

Identifiers

NCT03967457

CCQOL

Details and patient eligibility

About

This is prospective cohort study. All the patients with primary cervical cancer in the future three years in Peking Union Medical College Hospital will be included in this study. Before and after the major therapy (including at least radical hysterectomy and/or radiotherapy), the patients accept (1) the questionnaires survey about quality of life; (2) urodynamic testing; (3) rectum dynamics testing and (4) ovarian reserve function. The survival outcomes (disease-free survival and overall survival) will be supplemented as secondary objectives.

Enrollment: 10,000 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary uterine cervical carcinomas
• Aged 18 or older
• Accepting major therapy (including at least radical hysterectomy and/or radiotherapy) in the study center
• Informed consents delivered

Exclusion criteria

• Not meeting any of the inclusion criteria
• Not accepting any of the four kinds of evaluations for quality of life
• Recurrent patients
• Not achieving response after above major therapy