Comprehensive Yoga Therapy Based Lifestyle Prehabilitation Program for Women With Ovarian Cancer

M.D. Anderson Cancer Center

Status

Not yet enrolling

Conditions

Ovarian Cancer

Treatments

Other: Yoga Therapy for Nutritional, Physical, and Psychosocial Prehabilitation

Study type

Interventional

Funder types

Other

Identifiers

NCT06545604

2024-0374

Details and patient eligibility

About

To provide a comprehensive yoga therapy (CYT) program to patients with ovarian, fallopian tube, or primary peritoneal cancer who are scheduled to receive chemotherapy and then undergo surgery. Researchers want to learn about the effects of the program on patients' quality of life and other outcomes described below.

Full description

Primary Objectives:

To assess the feasibility of a CYT prehabilitation program in women with ovarian cancer scheduled to receive NACT and IDS. Feasibility criteria will include consent (30% of those approached) and study retention (60%) rates.

Secondary Objectives:

Examine the effects of the CYT program on physical conditioning as assessed by the 6 min walk test (6MWT) and sit to stand reps (30secSTS) compared with WLC.

Examine group differences in surgical outcomes including post op stay, readmission rate, post op morbidity, surgical site infection rate, transfusions, and time to first chemotherapy post operatively.

Examine group differences in patient-reported outcomes including QOL, fatigue, stress, sleep disturbances, mental health, social support, and mindfulness.

Examine if there are group differences in preoperative albumin level, vit D, magnesium levels.

Examine group differences and changes over time in microbiome biodiversity.

Examine group differences in body composition (sarcopenia) as measured by routine abdominal CT scans.

Explore the association between adherence to the components of CYT with ability to sustain behavior changes and between changes in lifestyle parameters with outcomes. This will be explored both within and across groups.

Enrollment

44 estimated patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Women with stage III-IV epithelial ovarian, fallopian tube, primary peritonal cancer with recommendations for NACT/IDS at recruitment.
Able to read, write, and speak English.
18 years of age or older.
Oriented to person, place, and time.
Access to internet connection.
Access to a tablet, laptop or computer or smart phone.
Plan for surgical intervention at MD Anderson Cancer Center
Performance status 0-2.

Exclusion criteria

Have completed chemotherapy.
Any major thought disorder (e.g., schizophrenia, dementia).
Any major communication barriers that would preclude being able to complete the intervention (e.g., visually or hearing impaired).
Extreme mobility issues (e.g., unable to get in and out of a chair unassisted).