Compuls-BED-Severity

Laval University

Status: Enrolling

Conditions: Binge-Eating Disorder

Treatments: Other: Observational

Study type: Observational

Funder types: Other

Identifiers

NCT05149859

2022-3743, 22144

Details and patient eligibility

About

• Binge Eating Disorder (BED) has been fairly recently introduced into the Diagnostic and Statistical Manual 5 psychiatric classification and its severity criteria are still not well established.
• Moreover, it remains unclear whether BED is associated with greater metabolic severity or more somatic comorbidities, especially in obesity.
• Improved BED severity staging could lead to a better definition of management strategies and , therefore, facilitate screening and care.

The investigators' hypothesis is that an improved assessment of the impulsivity-compulsivity spectrum, emotional regulation, attentional impairment and somatic or psychiatric comorbidities will result in a better distinction between the severe form of BED (e.g., highly impulsive and somatically complicated) from milder form (e.g., more compulsive and less somatically complicated).

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• men or women aged 1
• participants eligible for bariatric surgery (BMI>40, or BMI>35 with severe comorbidities)
• participants scheduled for medical evaluation and treatment of obesity at the IUCPQ Obesity Clinic (BMI≥30)
• participants scheduled for evaluation and treatment of BED at the CEPIA with obesity (BMI≥30)
• for the group with BED: positive BEDS-7 screen and Binge Eating Scale score >16;
• for the control group: have a negative BEDS-7 screen and Binge Eating Scale score<12
• be fluent in French and able to consent.

Exclusion criteria :

• participants with severe neurological disorder and/or major neurocognitive deficits;
• participants with previous bariatric surgery or with introduction or change of anti-obesity medication (liraglutide or naltrexone/bupropion) in the previous 3 months;
• participants who cannot read and/or understand French;
• participants under guardianship or curatorship;
• participants already included in a study with a conflict of interest with this study;
• inability to use a computer or iPad;
• inability to access an Internet connection or to visit one of the inclusion sites.

Secondary exclusion criteria:

• participants with a discordance between BEDS-7 (positive) and Binge Eating Scale (score ≤ 16) results found secondarily
• participants who did not participate in part of the assessments (e.g., self-questionnaires or neurocognitive tests) and participants with a rate of missing data>10%.

Trial design

200 participants in 2 patient groups

BED+ : Participants with obesity and binge eating disorder

Description:

Obesity is define by a BMI ≥ 30 kg.m-2 Binge eating disorder is defined by Binge Eating Disorder Screener (BEDS)-7 positive score and a Binge Eating Scale score \>16

Treatment:

Other: Observational

BED-: Participants with obesity but without binge eating disorder

Description:

Obesity is define by a BMI ≥ 30 kg.m-2 Binge eating disorder is defined by Binge Eating Disorder Screener (BEDS)-7 negative score and a Binge Eating Scale score \< 12

Treatment:

Other: Observational