Computational Fluid Dynamics Predicting Intraprosthetic Thrombus Formation and Progression Following EVAR

Central South University

Status: Completed

Conditions: Limb Graft Occlusion; Intraprosthetic Thrombus

Study type: Observational

Funder types: Other

Identifiers

NCT06701773

2024030373

Details and patient eligibility

About

Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR). Morphological metrics based on preoperative CTA have limited predictive value for these complications. This study aims to assess the potential of computational fluid dynamics (CFD) in predicting IPT formation and its progression to LGO after EVAR.

Enrollment: 72 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Aged 18 and above;
2. Patients undergone endovascular aneurysm repair;
3. Signed informed consent forms, willing to receive treatments.

Exclusion criteria

1. inflammatory aortic aneurysm;
2. patients diagnosed with connective tissue diseases;
3. patients diagnosed with atrial fibrillation;
4. patients lacking post-operative CTA;
5. Patients who are participating in other clinical projects;
6. Patients are not suitable to participate in this study.

Trial design

72 participants in 2 patient groups

Intraprosthetic thrombus Group

Description:

presence of intraprosthetic thrombus according to the postoperative CTA

Non-intraprosthetic thrombus Group

Description:

absence of intraprosthetic thrombus according to the postoperative CTA