Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

The Washington University

Status: Completed

Conditions: Subarachnoid Hemorrhage; Cerebral Vasospasm; Cerebral Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT00962546

HRPO 09-0950

Details and patient eligibility

About

Cerebral vasospasm is a devastating complication of subarachnoid hemorrhage after cerebral aneurysm rupture leading to cerebral ischemia and potentially cerebral infarction. The current gold standard diagnostic imaging study for cerebral vasospasm is catheter cerebral angiography, an invasive diagnostic procedure carrying a complication rate of 1-2% per procedure. Computed tomographic perfusion imaging (CTP) and computed tomographic angiography (CTA) are noninvasive diagnostic imaging studies frequently utilized in the evaluation of embolic and thrombotic cerebral infarct. The investigators hypothesize that CTP and CTA may be utilized as screening tools for cerebral vasospasm following aneurysmal subarachnoid hemorrhage requiring treatment and provide prognostic information.

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• subarachnoid hemorrhage after aneurysm rupture

Exclusion criteria

• renal insufficiency
• pregnancy
• contrast reaction

Trial design

4 participants in 1 patient group

CTA/CTP

Description:

Patients undergo CTA/CTP imaging prior to cerebral angiography