Computed Tomography (CT) Reconstruction for Axillary Lymph Node Structure (CTREP)

Peking University

Status: Completed

Conditions: Invasive Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT03247478

BCP20

Details and patient eligibility

About

This is a prospective, single-center, non-randomized, non-controlled observational study.

Full description

The negative predictive value of ultrasound for lymph node with neoadjuvant chemotherapy is low, magnetic resonance imaging (MRI) or PET/CT did not significantly improve specificity to axillary lymph node. The aim of this study is to determine performance of computed tomography (CT) reconstruction on evaluation of lymph node status after neoadjuvant chemotherapy in breast cancer patients.

Enrollment: 160 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Invasive breast cancer with axillary lymph node metastasis by confirmed by fine needle aspiration (FNA) or core needle biopsy (CNB).
• Underwent computed tomography (CT) reconstruction for assessment of axillary lymph node status before and after neoadjuvant chemotherapy (NAC).
• Attend the study voluntarily, sign the informed consent.

Exclusion criteria

• Contradiction for adjuvant chemotherapy.
• Contradiction for proceeding surgery.

Trial design

160 participants in 1 patient group

invasive breast cancer

Description:

Patients with invasive breast cancer who underwent computed tomography (CT) reconstruction of axillary lymph node for assessment of lymph node response after NAC are eligible for this study. Axillary lymph node metastasis is confirmed by fine needle aspiration (FNA) or core needle biopsy (CNB) at initial diagnosis.