Computed Tomography in Detecting Movement of the Esophagus in Patients Undergoing Radiation Therapy to the Chest

Temple University Health System (TUHS)

Status: Completed

Conditions: Unspecified Adult Solid Tumor, Protocol Specific

Treatments: Procedure: computed tomography

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00433524

P30CA006927 (U.S. NIH Grant/Contract)

FCCC-03604

CDR0000304723

Details and patient eligibility

About

RATIONALE: Comparing results of diagnostic procedures, such as computed tomography scan (CT scan), done before and after radiation therapy to help detect movement of the esophagus may help doctors plan the best treatment.

PURPOSE: This clinical trial is using CT scan to help detect movement of the esophagus in patients undergoing radiation therapy to the chest.

Full description

OBJECTIVES:

• Determine the inter- and intra-fraction movement of the esophagus using CT scans in patients undergoing thoracic radiotherapy.

OUTLINE: This is a pilot study.

Patients undergo CT scans at baseline and then once weekly during their scheduled radiotherapy sessions to determine esophageal placement while in the treatment position. CT scans are performed before and after the radiotherapy session. Pretreatment and post-treatment scans are compared.

PROJECTED ACCRUAL: A total of 15-30 patients will be accrued for this study.

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Planning to undergo definitive thoracic radiotherapy

PATIENT CHARACTERISTICS:

Age

• Not specified

Performance status

• Not specified

Life expectancy

• Not specified

Hematopoietic

• Not specified

Hepatic

• Not specified

Renal

• Not specified

PRIOR CONCURRENT THERAPY:

Biologic therapy

• Not specified

Chemotherapy

• Not specified

Endocrine therapy

• Not specified

Radiotherapy

• See Disease Characteristics
• No concurrent palliative thoracic radiotherapy

Surgery

• Not specified

Other

• Concurrent participation in other clinical trials allowed