Computer-assisted Diagnosis System Based on Linked Colour Imaging

Affiliated Hospital to Academy of Military Medical Sciences

Status

Unknown

Conditions

Computer-aided Diagnosis

Colorectal Polyp

Linked Color Imaging

Study type

Observational

Funder types

Other

Identifiers

NCT03359343

307-LCI-CAD

Details and patient eligibility

About

Linked color imaging (LCI)，a new endoscopy modality, creates clear and bright images by using short wavelength narrow band laser light. LCI can make red area appear redder and white areas appear whiter. Thus, it may be possible to distinguish adenoma and non-adenoma polyps based on color evaluation of LCI images. This study aimed to assess the correlation between histology results and LCI images. Moreover, the investigators conducted a pilot study to explore the clinical potential of LCI to distinguish adenoma and non-adenoma polyps and the accuracy of an automatic computer-aided diagnosis system using LCI imagine to predict histology polyps when compared to human experts physicians.

Full description

This study consists of a retrospective analysis and a pilot study. In the retrospective study, the investigators tried to find out an correlation between LCI images and histology results for polyp lesions. And a computer-aided analysis of the images was conducted to demonstrate the correlation objectively. Thereafter,a pilot study was performed to explore whether the previous correlation could be easily learned to distinguish adenoma and non-adenoma polyps by comparing the results of experts diagnosis of LCI image and non-experts. Also, in the pilot study, the investigators assessed the accuracy of an automate histology diagnosis method for polyp LCI images using the computer-aided system when compared to human experts physicians. Throughout the entire research, histology results are regarded as gold standard.

Enrollment

250 estimated patients

Sex

All

Ages

16 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

at least one polyp found during colonoscopy examination.

Exclusion criteria

poor quality of bowel preparation which impedes histology evaluation; previous resection of colon; inflammatory bowel disease; familiar adenomatous polyposis; Peutz-Jeghers syndrome or other polyposis syndrome.