Computer-Assisted Quantification of the Synovial Perfusion in Patients With Arthritis Using Two-Dimensional and Three-Dimensional Power Doppler Ultrasonography

Taichung Veterans General Hospital

Status: Unknown

Conditions: Synovitis

Study type: Observational

Funder types: Other

Identifiers

NCT00903903

IRB TCVGH No:C09048

Details and patient eligibility

About

The purpose of this study is to compare the data obtained by computer-aided quantification of the synovial perfusion in patients with arthritis using two-dimensional and three-dimensional power Doppler ultrasonography and the clinical data used to represent the degree of joint inflammation. Intra- and inter-observer reliability of this method will also be determined.

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with at least one painful swollen peripheral joint observed by a rheumatologist, including:

  • shoulder joints
  • elbow joints
  • wrist joints
  • metacarpophalangeal (MCP) AND
  • proximal interphalangeal (PIP) joints of hands, ankle joints, subtalar joints, mid-tarsal joints, MTP and PIP joints of feet

Exclusion criteria

• patients with active infection
• patients with concurrent malignant disease
• patients with a history of traumatic, septic, or cystal arthritis
• previous joint surgery, or isotopic synovectomy within the past 12 months before the study

Trial design

100 participants in 2 patient groups

1

Description:

RA patients with at least one active synovitis

2

Description:

Non-RA patients with at least one active synovitis