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Computer-Based Therapy for Mild Cognitive Impairment

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Posit Science

Status and phase

Completed
Phase 1

Conditions

Mild Cognitive Impairment

Treatments

Procedure: Computer-based training for Mild Cognitive Impairment (MCI)

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT00319943
OUT-108-2005

Details and patient eligibility

About

The purpose of this study is to determine the neuropsychological and neurophysiological impacts of a computer-based training program designed to improve the cognitive performance of patients with mild cognitive impairment (MCI).

Full description

The study is a randomized, double-blind, controlled trial of a computerized, cognitive intervention with three main goals: 1) to assess the magnitude of improvements in memory, language function, and cognitive function following computer training, 2) to investigate the neurophysiological mechanisms underlying such neuropsychological improvements, and 3) to demonstrate the feasibility of using this kind of computer-based therapy in older populations.

Sex

All

Ages

65 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

1)65 - 90 years of age 2)Meet definition for MCI including complaints of cognitive decline as indicated by patient report and/or informant report, and corroborated by clinician judgment and, the absence of dementia, defined as impairment of memory and at least one other domain of cognitive function.

3)Fluency in English 4)Willing to meet the time commitment of the study

Exclusion criteria

  1. Clinically significant cerebrovascular disease
  2. Individuals scheduled to begin acetylcholinesterase inhibitor (AChEI) therapy -

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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